A growing biotech company in Rockville, MD is looking to add a Lead Antibody Engineer to their team who has extensive knowledge in guided phage display and antibody discovery technology.

Key Responsibilities:

• Innovate new phage display techniques — including guided selection methods and epitope-focused approaches — to enhance platform capabilities beyond traditional processes.
• Utilize deep mutational scanning and NGS-based analysis to gain insight, guide library design, and create predictive models of antibody fitness landscapes.
• Create novel phage display selection methods for complex targets like membrane proteins and conformational epitopes.
• Contribute to intellectual property and field advancement through inventing and publishing high-impact research.
• Collaborate with structural biology to utilize cryo-EM, crystallography, and molecular dynamics data for informed engineering decisions.
• Incorporate AI/ML and computational tools into phage display processes, leveraging generative protein design and in silico affinity prediction to speed up lead discovery and optimization.

• PhD in Molecular Biology or related discipline.
• Proven experience in advanced phage display with focus on method development.
• Strong track record of impactful publications is a plus.
• Interest in working at the intersection of experimental and computational antibody engineering.